Dihydroergotoxine mesylate

CAS No. 8067-24-1

Dihydroergotoxine mesylate( Ergoloid Mesylates, Hydergine, Gerimal, CCK-179, CCK179 )

Catalog No. M19129 CAS No. 8067-24-1

It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dihydroergotoxine mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
  • Description
    Ergoloid Mesylates, also known as dihydroergotoxine mesylate, is a mixture of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine). Ergoloid mesylates is used as a treatment for dementia and Alzheimer disease. Ergoloid Mesylates stimulates dopaminergic and serotonergic receptors and blocks alpha-adrenoreceptors. Ergoloid Mesylates binds to the GABAA receptor Cl- channel, producing a reaction at the benzodiazepine site.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Ergoloid Mesylates, Hydergine, Gerimal, CCK-179, CCK179
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    Others
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    8067-24-1
  • Formula Weight
    673.82
  • Molecular Formula
    C33H47N5O8S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 31 mg/mL; 13.39 mM
  • SMILES
    CS(O)(=O)=O.CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Abdul M, et al. Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer. Acta Oncol. 2008;47(8):1546-50.
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